Research

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We study the core mechanisms of neuronal synaptic and circuit function including activity-dependent changes in synaptic strength and circuit connectivity, in key regions of the brain that mediate - 

1. Memory-guided behaviors

2. Reward-seeking behaviors.

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Our goal is to probe the molecular, synaptic and neuronal circuit malfunctions that are often found in disease- we are particularly interested in the functional characterization of mutations that are commonly found in patients with neuropsychiatric disorders like autism spectrum disorders and schizophrenia.

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Some of the tools and techniques we routinely use in the lab are- mouse genetics, gene editing tools including the CRISPR-Cas9 system, Opto/chemo genetics combined with intersectional genetic and circuit mapping viral tools, in-vitro whole-cell patch-clamp electrophysiology, transcriptomics, and rodent behavior. 

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